Description
Fighting neuroinflammation Nasal administration for direct access. The nasal delivery system ensures bioavailability across the blood-brain barrier. Microglia Microglia are a specialised population of macrophage-like cells present in the central nervous system (CNS) and are considered immune sentinels. Microglial cells are trained to eliminate threats such as: √ LPS endotoxins √ antigens √ autoantigens At the same time as suppressing all aggressions, microglia release mediators such as pro-inflammatory cytokines to orchestrate repair and subsequent organisation. Rg3 modulates microglia and fights neuroinflammation Ginsenoside Rg3 is a steroidal saponin that is highly enriched in Korean red ginseng. It has a wide range of pharmacological activities. The nasal delivery system ensures bioavailability across the blood-brain barrier. Effects √ Rg3 significantly reduces the number of activated microglial cells and the release of pro-inflammatory cytokines. √ Rg3 stabilises mast cells √ Rg3 interferes with the interaction between mast cells and microglia Indication All types of neuroinflammation: √ autism √ neurodegenerative diseases √ (post-)infection √ LPS-induced neuroinflammation √ Rg3 prevents neuronal damage related to adrenal stress and fatigue