Description
A natural solution for managing pain and inflammation √ Synergy of patented PEA Levagen+ ™ and Boswellia serrata. √ Clinically proven efficacy for chronic and inflammatory conditions (e.g. osteoarthritis, migraines...). √ Acts on pain and inflammation and improves recovery. √ Suitable for a wide range of patients suffering from chronic pain or specific conditions. Anti-inflammatory and analgesic PEA Calm combines the benefits of patented palmitoylethanolamide (PEA) Levagen+ and Boswellia serrata . This supplement is a powerful natural analgesic, acting on various types of pain and inflammation. Thanks to its patented Levagen+™ form, it offers increased bioavailability and clinically proven results. NATURA Medicatrix has chosen a unique patented form of PEA! √ It is water-soluble (Levagen+™) and much better absorbed by your body compared with traditional PEA. √ The Levagen+™ PEA from NATURA Medicatrix is 1,75x better absorbed than classic PEA. √ A n ingredient of high quality, whose effectiveness has been successfully evaluated in several clinical studies. Active ingredients Palmitoylethanolamide (PEA) : naturally produced by the body, it reduces pain and inflammation by acting on various receptors of the endocannabinoid system. √ Downregulates mast cell degranulation, via an ALIA effect (prevents immune system cells from releasing inflammatory mediators); √ Entourage effect : PEA inhibits the enzymes FAAH (fatty acid hydrolase) and MAGL (monoacylglycerol lipase), which limits the breakdown of the endocannabinoids anandamide and 2-AG and therefore increases their levels. These, in turn, activate the CB1, CB2 and TRPV receptors (entourage effect); √ PEA also directly stimulates the PPAR-α and GPR55 receptors. All these mechanisms result in powerful anti-inflammatory and analgesic effects. Boswellia s errata √ Rich in boswellic acids, it inhibits enzymes responsible for producing inflammation (notably 5-LOX); √ This extract, complementary to the effect of PEA, provides support against osteoarthritis and inflammatory conditions. Therapeutic applications √ Acute pain (osteoarthritis flare-ups, migraines, period pain); √ Chronic pain (endometriosis, fibromyalgia); √ Neuropathic pain (diabetic neuropathy, sciatica, carpal tunnel syndrome, pudendal neuralgia) √ Beneficial for the gut (reduces intestinal permeability, reduces mucosal inflammation, useful in cases of IBD); √ Antiallergic (also useful in cases of MCAS, histamine intolerance); √ Neuroprotective (Parkinson's, Alzheimer's, ALS); √ Improved muscle recovery and reduced inflammation after exercise. Levagen, a well-studied PEA A randomised, double-blind controlled study was conducted to demonstrate the efficacy of Levagen ™ on osteoarthritis symptoms. Doses of 600 mg and 300 mg were shown to be statistically significant (compared with placebo) on: √ Total WOMAC score; √ pain, stiffness and joint function; √ anxiety. Total WOMAC score by group. PEA reduces pain from 300 mg per day. The effect is improved with 600 mg of PEA per day. Levagen+ ™ PEA has also been studied in other areas: headaches, peripheral neuropathies in diabetic patients, sleep, COVID-19, cold and flu symptoms, allergic rhinitis, the microbiome and menstrual pain. Target patients Patients suffering from chronic and inflammatory pain. Those affected by neurodegenerative diseases or digestive disorders. People experiencing neuropathic pain or inflammation linked to chronic conditions. An excellent alternative to NSAIDs, without the side effects. An alternative to CBD (similar mechanisms), without the risk of drug interactions associated with CBD.
